Liver fibrosis is one of the processes that occurs when the liver is damaged.
Fibrosis is both a sign of liver damage and a potential contributor to liver failure via progressive cirrhosis of the liver.
Liver fibrosis is the excessive accumulation of extracellular matrix proteins including collagen that occurs in most types of chronic liver diseases. Advanced liver fibrosis results in cirrhosis, liver failure, and portal hypertension and often requires liver transplantation. Our knowledge of the cellular and molecular mechanisms of liver fibrosis has greatly advanced. Activated hepatic stellate cells, portal fibroblasts, and myofibroblasts of bone marrow origin have been identified as major collagen-producing cells in the injured liver. These cells are activated by fibrogenic cytokines such as TGF-beta1, angiotensin II, and leptin. Reversibility of advanced liver fibrosis in patients has been recently documented, which has stimulated researchers to develop antifibrotic drugs. Emerging antifibrotic therapies are aimed at inhibiting the accumulation of fibrogenic cells and/or preventing the deposition of extracellular matrix proteins. Although many therapeutic interventions are effective in experimental models of liver fibrosis, their efficacy and safety in humans is unknown. This review summarizes recent progress in the study of the pathogenesis and diagnosis of liver fibrosis and discusses current antifibrotic strategies.
There are 13 liver cancer treatments Liver Cancer Treatments – Surgical Resection http://www.livercancer-stage.com/liver-cancer-treatments-surgical-resection/ Liver Cancer Treatments – Chemotherapy http://www.livercancer-stage.com/liver-cancer-treatments-chemotherapy/ Liver Cancer Treatments – Chemoembolization http://www.livercancer-stage.com/liver-cancer-treatments-chemoembolization/ Liver Cancer Treatments- Alcohol Injection,Hepatic Artery Infusion,Interstitial Laser Photocoagulation and Microwave,Portal Vein Embolization ,Isolated Liver Perfusion ,Liver Transplantation more post of 13 liver cancer treatments can be found in http://www.livercancer-stage.com/category/liver-cancer-treatments i personnaly suggestion is that before decides the liver cancer treatments you are going to choose, do some study on them, and choose the right treatments for you.
Tags: liver cancer, Liver Cancer stage, liver cancer stage Cirrhosis, Liver Cancer Stage Fibrosis, liver cancer stage four, Liver Cancer Stage Inflammation